In the ever-evolving world of Old School Run Escape (OSRS), bossing has cemented itself as one of the most rewarding and profitable activities for players looking to rake in millions of GP. Gone are the OSRS Gold days when the best moneymaking methods involved flax picking, yew cutting, or running law runes. PvM (Player vs. Monster) content is now king—offering not just massive loot, but thrilling challenges that test your mechanical skill and game knowledge.

With new bosses introduced, old ones reworked, and drop tables constantly rebalanced, 2025 is a golden age for PvM enthusiasts. This list isn’t just about raw gold per hour—it’s a mix of profit, difficulty, accessibility, and most importantly—how fun the fights are. So whether you're a solo grinder or a raid junkie, there’s something here for you.

Let’s dive into the top 10 PvM bosses for money-making in OSRS.

#10 – Vorkath: The Money Dragon

Requirements: Completion of Dragon Slayer II

Difficulty: Moderate

Profit: ~2.5–3.5M GP/hr

Vorkath has stood the test of time as a steady moneymaker. Thanks to high-value drops like superior dragon bones, dragon bolts (unf), and blue dragonhide, this solo dragon offers reliable income in every kill. His instanced nature ensures no competition or crashers, and once you master his mechanics, the kills become smooth and efficient.

Why it’s great:

Consistent and low-stress

Always available

Great for casual bossers or alchemists looking to AFK alch between attacks

#9 – Venonatis (and Spindle)

Requirements: None (but Wilderness knowledge is crucial)

Difficulty: Easy to Moderate

Profit: ~4–5M GP/hr

Wilderness PvM isn’t for the faint of heart, but Venonatis and her weaker form, Spindle, offer tremendous returns. Venonatis has a chance to drop the Voidwaker gem (worth ~50M), and even her standard loot table is strong enough to make the risk worth it.

Why it’s great:

High-risk, high-reward

Low barrier to entry

Potential jackpot drops

Just make sure you have escape routes mapped out, bring untradeables, and expect the occasional encounter with PKers.

#8 – Phantom Muspah

Requirements: Secrets of the North quest

Difficulty: Moderate

Profit: ~3–5M GP/hr

Phantom Muspah is often described as a solo-friendly cousin to Vorkath. It's instanced, features smooth and reactive mechanics, and has a notable drop in the Ventor’s Shard (~14.5M GP, 1/100 drop rate).

Why it’s great:

Great for improving PvM fundamentals

Jackpot drop potential

Easily accessible and scalable

A perfect boss for intermediate players looking to step up their mechanical skill while earning a solid income.

#7 – Fosani’s Nightmare

Requirements: High combat stats and strong gear

Difficulty: High

Profit: ~4–6M GP/hr

Fosani’s Nightmare is a solo version of the Nightmare of Ashihama and is considered one of the most intense 1v1 boss fights in OSRS. It punishes mistakes but rewards skill and focus with items like the Inquisitor’s set and Nightmare staff upgrades.

Why it’s great:

One of the most engaging solo challenges

High-end drops that can exceed 100M+

Mastery feels incredibly satisfying

Not for beginners, but experienced PvMers will love the rewarding challenge.

#6 – Tombs of Amascut (ToA)

Requirements: Desert Treasure II and scalable gear

Difficulty: Scales from Moderate to High

Profit: ~4–7M GP/hr

ToA is one of OSRS’s most versatile raids, thanks to its invocation system which lets players scale difficulty and rewards. It's soloable, group-friendly, and offers some of the most lucrative drops in the game, including Tumeken’s Shadow (~1.1B GP).

Why it’s great:

Scalable for all skill levels

Raid-style loot with jackpot potential

Excellent raid introduction for new players

Whether you’re soloing or running with friends, ToA delivers consistent profits and endless variety.

#5 – Chambers of Xeric (CoX)

Requirements: High combat and utility skill levels

Difficulty: Medium to High

Profit: ~4–6M GP/hr

The original OSRS raid is still going strong. Twisted Bow (~1.6B GP) remains one of the most valuable items in the game, and CoX's diverse loot table—featuring Ancestral pieces, the Dragon Hunter Crossbow, and Kodai wand—keeps every drop exciting.

Why it’s great:

Incredibly replayable

Viable for both casual and hardcore raiders

Great team content

Still one of the best GP/hr raids for seasoned groups.

#4 – Nex

Requirements: Frozen Door miniquest and strong DPS gear

Difficulty: Moderate

Profit: ~5–8M GP/hr

Nex, the boss with a reputation for stacking loot, is famous for high-value drops like the Zaryte Crossbow and Zaryte Vambraces. It’s best done in small, efficient teams to maximize kill speed and loot share.

Why it’s great:

Massive drop potential

Reasonable difficulty

Great for mid-to-high level players with decent gear

Expect fierce competition, but the rewards speak for themselves.

#3 – Vardorvis

Requirements: Desert Treasure II

Difficulty: High

Profit: ~6–8M GP/hr

Vardorvis is one of the mechanically toughest solo bosses in OSRS, but those who master him are rewarded with high-value drops, including the Soulreaper Axe components. Fast-paced, mechanically rich, and solo-only, Vardorvis is a must-learn for high-level PvMers.

Why it’s great:

One of the best solo boss experiences

Big drops and consistent loot

Steep learning curve with huge payout

Ideal for those looking to improve prayer flicking and movement skills.

#2 – Theatre of Blood (ToB)

Requirements: High stats, top-tier gear, team coordination

Difficulty: High

Profit: ~6–10M GP/hr

ToB remains a pinnacle of OSRS PvM content. From the Scythe of Vitur (~1.8B GP) to Justiciar pieces, the loot table is both valuable and iconic. It demands teamwork, communication, and precision—but that’s what makes it so satisfying.

Why it’s great:

Top-tier team PvM experience

Insane drop potential

Huge satisfaction factor

If you've got a team, this is one of the best PvM activities in the game—bar none.

#1 – The Rest of the Desert Treasure II Bosses (Zebak, Duke Sucellus, Leviathan)

Requirements: Desert Treasure II

Difficulty: Moderate to High

Profit: ~5–8M GP/hr

Zebak, Sucellus, and the Leviathan round out the Desert Treasure II roster, and each is a worthy goldmine. All of them drop powerful uniques like the Virtus robe set and ring upgrades that fetch huge sums on the Grand Exchange.

Why it’s great:

No need to wait on teams—solo-friendly

Cycle between bosses for variety

High return for skilled players

Their accessibility, skill ceiling, and loot tables make them the most rewarding PvM content in OSRS right now.

Final Thoughts

Bossing in OSRS has evolved into an art—and a science. With so many bosses catering to different skill levels and playstyles, there's never been a better time to start PvMing for profit. Whether you're stacking millions an hour at Nex or learning mechanics at Phantom Muspah, the most important thing is to enjoy the grind.

Profit is great. Fun is better. The bosses you like fighting will always be the most rewarding in the long run.

So get your gear, sharpen your skills, and start farming—because Gielinor isn’t going to loot itself.